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DeSoto House Hotel
The DeSoto House Hotel opened on April 9, 1855, in Galena, Illinois, and was billed as the “Largest Hotel in the West.” The DeSoto House Hotel was the center of Galena’s social and political activities. One of its most notable visitor was President Abraham Lincoln, who spoke from its Main Street balcony in July 1856. Later, General Ulysses S. Grant used rooms 209 and 211 of the hotel as his presidential campaign headquarters.
Stay in the beautiful, historic DeSoto House Hotel today!