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The ALS Therapy Development Institute (ALS TDI) is the world's most comprehensive drug discovery lab focused solely on ALS.

Led by drug development experts and people with ALS, our Watertown, Massachusetts-based lab is funded by a global network of supporters unified to end ALS. Our mission is to discover and invent effective treatments for ALS.

ALS TDI is 100 percent focused on research to invent and discover treatments to slow, stop, and reverse ALS. The ALS TDI lab executes research encompassing all areas of ALS target and drug discovery research – including preclinical, clinical, and translational – under one roof. This makes our research extremely efficient and allows for seamless collaboration across all areas. 

ALS TDI’s main role is to be the drug discovery engine for ALS. We do the time-intensive research that is needed to invent and discover treatments that show enough efficacy to be advanced to trials.

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