The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated over $3.1 million dollars to the ACC, funding 74 research projects. 100% of all participant-raised dollars are donated directly to cancer research.
Our 2026 Fundraising Goal
$183,226
Raised of $300,000
Match Challenge Round Two
August 24th, 2026 until funding is exhausted
$9,540 remaining as of 9:00 AM 8/30/2026
The first $50,000 in donations received will be matched, dollar for dollar, starting Monday, August 24 until funds are exhausted. Share your personal and team fundraising pages with family and friends.
Together we can make a difference and double our impact!
Thank You Match Challenge Partner
Team Building Promotion On Now!
Our 2025 Event Raised $350K!
Our Leaderboards
Top Fundraisers
Top Individuals (221)
View AllDavid Wellborn
$15,275.00 raised of $20,000.00
Bo Ebby
$13,900.00 raised of $15,000.00
Tina Wilson
$9,752.00 raised of $1,000.00
Liz Lewis
$6,360.00 raised of $2,500.00
Top Teams (26)
View AllKeystone State Ride
$67,121.60 raised of $80,000.00
Team BC
$27,379.55 raised of $30,000.00
Team Zayde
$15,012.00 raised of $18,000.00
Mission Melanoma
$11,324.80 raised of $10,000.00
DTeam
$11,006.00 raised of $15,000.00
Donate To an Indvidual or a Team
Donate NowBreakthroughs in Action
Join Us to Make a Difference!
