The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated $2,825,000 to the ACC, funding 63 research projects. 100% of all participant-raised dollars are donated directly to cancer research.

Our 2025 Fundraising Goal
$14,859
Raised of $300,000
Thank You To Our Fundraisers!
Top Individuals
View AllDrew Costello
$5,050.00 raised of $500.00
Richard Adler
$2,550.00 raised
Christopher Hall
$1,550.00 raised of $1,000.00
Gail Seligson
$706.00 raised of $2,500.00
Bo Ebby
$550.00 raised of $10,000.00
Top Teams
View AllKeystone State Ride
$1,883.53 raised of $30,000.00
Team Zayde
$950.00 raised of $18,000.00
Team BC
$950.00 raised of $20,000.00
Beam of Life
$450.00 raised of $10,000.00