The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated $2,825,000 to the ACC, funding 63 research projects. 100% of all participant-raised dollars are donated directly to cancer research.
Our 2025 Fundraising Goal
$216,680
Raised of $300,000
Meet the Match Challenge
Meet the Match Challenge Round Two has begun!
Double the impact of your donation!
The first $50,000 in donations received will be matched, dollar for dollar, from now through Wednesday, August 27 (11:59pm). Share your personal and team fundraising pages with your family and friends – every dollar makes a difference!
MATCH CHALLENGE PARTNER: The Zent Family Foundation
$8,769 remaining funds, as of 8:00 AM, Thursday, August 21st, 2025
Breakthroughs in Action
Thank You To Our Fundraisers!
Top Individuals
View AllBruce Levine
$27,440.00 raised of $30,000.00
Lynn Schuchter
$25,935.76 raised
Bo Ebby
$13,400.00 raised of $15,000.00
William Wilson
$12,090.00 raised of $1,000.00
Lou Starzl
$12,075.00 raised of $12,500.00
Top Teams
View AllMission Melanoma
$51,270.76 raised of $10,000.00
Keystone State Ride
$46,170.53 raised of $30,000.00
CARs Pedaling For Cures
$29,065.00 raised of $30,000.00
Team BC
$19,215.00 raised of $20,000.00
Team Krieger
$11,000.00 raised of $10,000.00
Donate To an Indvidual or a Team
Donate NowJoin Us to Make a Difference!
